German researchers recently identified a new haplotype that affects holstein calves known as haplotype associated with Cholesterol Deficiency (HCD). Homozygous animals are born with no cholesterol and survive only a few months.
Heterozygotes have reduced cholesterol and survive only a few months. Heterozygotes have reduced cholesterol. The particular haplotype carrying the defect is difficult to track because a normal version and a recently mutated version are both frequent.
To learn more about where this haplotype traces back to, click here. CDCB identifies animals on a 0-4 scale.
0. Non-carrier: free of HCD
1. Carrier: haplotype confirmed with pedigree information
2. Homozygous: confirmed on both sides of pedigree
3. Suspect carrier: haplotype origin could not be confirmed from pedigree
4. Suspect homozygous: probable carrier and may be homozygous; origin of haplotypes could not be confirmed from pedigree
Listed below are the small portion of the Accelerated Genetics active marketed line-up that are confirmed carriers of HCD.
- 014HO07627 Sanders HCD1
- 014HO07464 Dusk HCD1
- 534HO00032 Kool HCD1
- 534HO00010 Cashcoin HCD1
- 534HO00009 Cashmoney HCD1
- 014HO07449 Ocean Pp HCD1
- 534HO00021 Prodigy-Red HCD1
The Accelerated Genetics website can be your trusted first choice to identify sires impacted with HCD across all studs. Below is a step by step of how to do so.
- Visit the Accelerated Genetics advanced search by clicking here.
- Click the red “advanced search” button.
- Click the “Status/Studs ” tab. A list of traits and boxes should appear
- In the second column, the fourth option down is Haplo Types, check the box to the right of it so that it turns blue with a checkbox in it.
- In the third column below the header Marketing Organization, check the box next to all studs.
- Then click search.
- After you click on the search box, sires from all studs will appear. A column called Haplo_Type will appear on the far right side that show which Haplotypes each bull is identified with.
Chelsey Johnson, Accelerated Genetics
